DAPAGLIFLOZIN PLUS CALORIE RESTRICTION BOOSTS REMISSION RATES IN ADULTS WITH TYPE 2 DIABETES AND OBESITY

By Dr. Priyom Bose, Ph.D.

A multicentre trial in China finds that combining SGLT-2 inhibitors with calorie restriction improves remission, weight loss, and metabolic health without added adverse effects

A recent BMJ study conducted a randomized trial to evaluate whether a combined therapy of dapagliflozin and calorie restriction had better effectiveness over only calorie restriction on the remission of T2D.

T2D prevalence and treatments

Approximately 422 million adults worldwide develop T2D. However, this condition can be reversed through weight management and dietary intervention.  The DiRECT trial findings indicated that intensive dietary intervention reduced 10% body weight in 46% of the diabetic participants.

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2025-01-24T15:46:15Z